How REMICADE Works

REMICADE is a biologic therapy that recognizes, attaches to, and blocks the action of a protein in your body called tumor necrosis factor alpha (TNF-alpha). TNF-alpha is made by certain blood cells in your body.

• The immune system protects the body by responding to “invaders” like bacteria, viruses, and other foreign matter that enter your body by producing antibodies and putting them into action to fight off the “invaders.”
• In plaque psoriasis, rheumatoid arthritis, psoriatic arthritis, adult Crohn’s disease, pediatric Crohn’s disease, ulcerative colitis, and ankylosing spondylitis, TNF can cause your immune system to attack healthy tissues in your body and cause inflammation and damage. 
• If these diseases are untreated, it can cause permanent damage to the body’s bones, cartilage, and tissue.
• REMICADE will not cure inflammatory disorders, such as plaque psoriasis, rheumatoid arthritis, psoriatic arthritis, adult Crohn’s disease, pediatric Crohn’s disease, ulcerative colitis, and ankylosing spondylitis, but blocking TNF-alpha may reduce the inflammation in your body.

For more specific information on how REMICADE works in specific inflammatory disorders, please visit the following resources:

• How REMICADE Works to Treat Plaque Psoriasis
• How REMICADE Works to Treat Rheumatoid Arthritis
• How REMICADE Works to Treat Psoriatic Arthritis
• How REMICADE Works to Treat Adult Crohn’s Disease
• How REMICADE Works to Treat Ulcerative Colitis
• How REMICADE Works to Treat Ankylosing Spondylitis